Prophase is the first phase of M phase in which chromatids condense, and sister chromatids appear, and spindle fibres form. Afterwards, sister chromatids of each chromosome appear.
Chromatin converts into discrete chromosomes. During the prophase, chromatin appears in a thick and condensed form. It is the first phase in which cell starts its nuclear division. Prophase is one of the phases of mitotic phase of the meiosis and mitosis. Side by Side Comparison – Prophase vs Metaphase in Tabular Form Similarities Between Prophase and Metaphaseĥ. Prophase is followed by metaphase and during the metaphase homologous chromosomes are arranged in the centre of the cell (equatorial plate), and the spindle fibres are attached to the chromosomes at the centromeres. Prophase is the first phase of M phase in which cell stops growth and starts to nuclear division. M phase proceeds via four main phases namely prophase, metaphase, anaphase and telophase. Mitotic phase or the M phase describes the nuclear division of the cell. Interphase, M phase and cytokinesis are three major phases of cell cycle.
#Prophase mitosis series#
The key difference between prophase and metaphase is that, in prophase, chromosomes condense and the spindle fibre forms while ,in metaphase, chromosomes line up in the centre of the cell and centromeres attach to the spindle fibres.Ĭell cycle refers to the series of events happening in a cell till it produces new cells. Prophase is the first phase and metaphase is the second phase of the M phase in the cell cycle.
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